Tedstehr
Distinguished member
- Joined
- Aug 25, 2017
- Messages
- 199
- Reason
- PALS
- Diagnosis
- 08/2017
- Country
- CA
- State
- BC
- City
- New Westminster
I hope some of you smart people (you know who you are!) can help me understand what ALS is in laymen's terms. Here is what I think - your feedback and corrections would be great.
ALS is an over production of a neuro transmitting chemical that causes neurons to fire. This over production in upper motor neurons (between the brain and spine) causes excessive firing, which cramps or stiffens their connected muscles and causes lack of control. The excessive firing in the lower motor neurons (from the spine to the muscles) causes fasiculations and muscle wasting. And because of the free radical oxygen molecules present in the synaptic gaps where the firing occurs, the sparking oxidizes or burns out the gaps, causing neuron death.
ALS is when both the upper and lower motor neurons are involved.
Thanks for feedback all!
ALS is an over production of a neuro transmitting chemical that causes neurons to fire. This over production in upper motor neurons (between the brain and spine) causes excessive firing, which cramps or stiffens their connected muscles and causes lack of control. The excessive firing in the lower motor neurons (from the spine to the muscles) causes fasiculations and muscle wasting. And because of the free radical oxygen molecules present in the synaptic gaps where the firing occurs, the sparking oxidizes or burns out the gaps, causing neuron death.
ALS is when both the upper and lower motor neurons are involved.
Thanks for feedback all!