Does ALS cause pain and discomfort in the hands? My hands are sore at times and even the joints feel kind of sore--not stiff! My fingers are not cramping and I have no weakness. The pain is not severe and does not limit movement. Any advice. I have a 3 year old I lift all of the time and I do check my strength in my hands(YEAh I know stupied) quite often, too---maybe I am just irritating them.