October 2016

Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

Researchers at St. Jude Children's Research Hospital have discovered the way toxic proteins linked to the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) incapacitate membrane-less organelles inside cells.

CNS10-NPC-GDNF for the Treatment of ALS

Condition: Amyotrophic Lateral Sclerosis
Intervention: Biological: Stem cell (HPC) implantation
Sponsor: Cedars-Sinai Medical Center
Not yet recruiting - verified October 2016

New Insights into Amyotrophic Lateral Sclerosis (ALS)

‘RNA based therapy as a treatment for amyotrophic lateral sclerosis (ALS)’ ALS ... Paul Taylor, Howard Hughes Medical Institute and St. Jude Children's Research Hospital; John P. Donohue, Manuel Ares Jr., UC Santa Cruz; and Steven Finkbeiner, Gladstone ...

ALS study reveals role of RNA-binding proteins

Although only 10 percent of amyotrophic lateral sclerosis cases are hereditary ... is an independent federal agency that supports fundamental research and education across all fields of science and engineering. In fiscal year (FY) 2016, its budget is ...

Toxic peptides disrupt membrane-less organelles in neurodegenerative disease

Scientists reveal how toxic peptides that arise due to amyotrophic lateral sclerosis and frontotemporal dementia target the integrity of membrane-less organelles and trigger disease. Researchers at St. Jude Children's Research Hospital have discovered the ...

Les Turner ALS Walk for Life on Track to Raise $1M for Research, Patient Services, Education

The Les Turner ALS Foundation had about 7,000 people on more than 200 teams support those affected by amyotrophic lateral sclerosis (ALS ... ALS Foundation was founded in 1977 to support research, patient care, and education about ALS, a rapidly ...

ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors

Condition: Lymphoblastic Lymphoma
Interventions: Drug: Rabbit Anti－human Thymoglobulin (r-ATG); Drug: Placebo
Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Recruiting - verified October 2016

Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered ALS-008176 Regimens in Adult Participants Hospitalized With Respiratory Syncytial Virus

Condition: Respiratory Syncytial Viruses
Interventions: Drug: ALS-008176; Drug: Placebo
Sponsor: Janssen Research & Development, LLC
Suspended - verified January 2017

11th Anniversary of ‘Tradition of Hope’ Gala Raises Funds for ALS

Augie’s Quest announced the 11 th annual ‘Tradition of Hope’ gala event will be held Oct. 15 at the Beverly Hilton Hotel to raise funds for amyotrophic lateral sclerosis (ALS) research. Augie’s Quest is a cure-driven nonprofit effort dedicated to ...

VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies

(2016) VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies ... VAChT antibody (vesicular acetylcholine transporter; BIOMOL Research lab, Plymouth Meeting, PA; 1:400 dilution), raised in different ...

October 2016

Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

CNS10-NPC-GDNF for the Treatment of ALS

New Insights into Amyotrophic Lateral Sclerosis (ALS)

ALS study reveals role of RNA-binding proteins

Toxic peptides disrupt membrane-less organelles in neurodegenerative disease

Les Turner ALS Walk for Life on Track to Raise $1M for Research, Patient Services, Education

ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors

Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered ALS-008176 Regimens in Adult Participants Hospitalized With Respiratory Syncytial Virus

11th Anniversary of ‘Tradition of Hope’ Gala Raises Funds for ALS

VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies

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October 2016

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