Bone Marrow Transplantation (BMT) and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance
Condition: Kidney Transplantation
Interventions: Biological: Antithymocyte globulin (ATG); Drug: Fludarabine; Drug: Low dose Pre-transplant cyclophosphamide; Radiation: Total Body Irradiation; Drug: Acetaminophen; Drug: Diphenhydramine; Drug: Methylprednisolone; Biological: Bone Marrow; Drug: MESNA; Drug: Mycophenolate mofetil (MMF); Drug: Prednisone; Drug: Filgrastim; Drug: High dose post-transplant cyclophosphamide
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)
Interventions: Biological: Antithymocyte globulin (ATG); Drug: Fludarabine; Drug: Low dose Pre-transplant cyclophosphamide; Radiation: Total Body Irradiation; Drug: Acetaminophen; Drug: Diphenhydramine; Drug: Methylprednisolone; Biological: Bone Marrow; Drug: MESNA; Drug: Mycophenolate mofetil (MMF); Drug: Prednisone; Drug: Filgrastim; Drug: High dose post-transplant cyclophosphamide
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); Immune Tolerance Network (ITN)