I picked up Perlmutter's "Better Brain Book" last week. It has a chapter on his program for ALS, which looks to be much the same as what he does for Parkinson's. I've been seeing a holistically oriented MD who has been wanting to try Perlmutter's program on me. This doctor has had good results with it for PD. So I've started the glutathione IV injections 3 days/week for the last week and a half. Hard to say if I'm seeing improvement, my speech is somewhat variable anyway. I've had a couple of good days and some bad ones too. No improvement in hand strength. We'll need more time to see if it is helping.
My wife is learning to do IVs so she can do it for me at home - the doctor's office is an hour's drive away. He is very supportive and is teaching her. I'm not sure where we will get the glutathione and IV supplies, presumably we can get them from the same place the doctor does, maybe with a prescription. Probably will be a couple more weeks before we are ready to transition to doing it at home.
Joel has reported that he had good results with IV glutathione a few years ago. Search on the forums for glutathione and you can find some discussion. He took a somewhat higher dose. Perlmutter says he does 1400 mg 3 times a week. I think Joel did that much 6 times a week. I am now doing 1600 mg 3 times a week. My doctor is also putting some B vitamins and magnesium in the mix. The magnesium causes hot flashes, he says it opens up the blood vessels so perhaps will help the glutathione to penetrate better.
I should add that the conventional medical wisdom is that IV glutathione probably won't work because not enough gets across the blood brain barrier into the nerve cells that are affected by ALS. However this is a pretty high dose, so maybe some does get across into the nerves; and also, the body is complicated and ALS is largely a mystery, so it is possible it could help via some other pathway. I read some research once hinting that ALS may be associated with problems with blood vessels. Or there was that one last week about ALS patients having problems with their thymus glands. There could be a lot of things going on, glutathione is a good antioxidant and could be helpful for many different conditions.