LatinoLoco
Member
- Joined
- Mar 23, 2010
- Messages
- 22
- Reason
- Learn about ALS
- Country
- CA
- State
- On
- City
- Toronto
Thank you to all who contributed to my previous thread. This thread is pretty much just curiosity on my part.
While conducting some searches online with regards to my "atrophy/injury" concerns, I bumped into some information on various types of focal muscular atrophy causes such as LMN pathologies, infections, trauma and entrapments to name a few. What caught my attention and sparked my curiosity was the mention of "Anterior horn cell diseases" such as Monomelic Amyotrophy and how they can cause significant wasting of a limb, but patients may have little to no weakness. How is this possible in this particular disease where as in ALS significant wasting of a limb (even a tiny bit of wasting) would causes debilitating weakness? Is it simply because Motor neurons are not destroyed in such diseases even though the atrophy is very real? Your knowledge in this topic is very welcome folks. Thanks.
While conducting some searches online with regards to my "atrophy/injury" concerns, I bumped into some information on various types of focal muscular atrophy causes such as LMN pathologies, infections, trauma and entrapments to name a few. What caught my attention and sparked my curiosity was the mention of "Anterior horn cell diseases" such as Monomelic Amyotrophy and how they can cause significant wasting of a limb, but patients may have little to no weakness. How is this possible in this particular disease where as in ALS significant wasting of a limb (even a tiny bit of wasting) would causes debilitating weakness? Is it simply because Motor neurons are not destroyed in such diseases even though the atrophy is very real? Your knowledge in this topic is very welcome folks. Thanks.