My grandfather died from ALS and my mom probably has it (my parents refuse to discuss it) so I may be more sensitive about the disease. Will anyone tell me what their initial symptoms were? I know many have twitching, tripping....but has anyone been walking or running and although your legs are not tired, they just decide they want a rest, although your brain telling them to keep going? sort of like they are not connected to your body and have a mind of their own? Am I making sense? Thanks - I'm new to this and while I'm doing a ton of research on my own, I'd rather speak with people.:?: