Thanks to all replies! I just returned from my 5-week visit. They tested everything, since I now have a 1-month supply of full dose and don't return for a month. They did not test hand strength each visit. But, over the 5 weeks of the trial to date, right hand went from 60 to 57. Left hand 25 to 21. I don't know if this is significant? There is no loss of lung capacity. I have essentially the same capacity since MAYO clinic visit in March, so that is good. I had fallen on Friday night and stubbed my middle finger on right hand and so my right hand might still be slightly stronger, since finger was sore for the grip test. I did the tests pre-meds on Tuesday am, then took 2 tablets and tested again 3 hrs later. Left hand declined to 17 for the second test, but right hand stayed the same. I don't have all the muscle data on the feet, ankles, etc. Nurse thought everything was generally the same 3 hrs after taking the meds. I feel like all body movements got slower, walking steps the most noticeable. best wishes.