Good morning,
I'm new to this forum as a member, but have reading you for a while and know enough to be really scared. I am female of 32 years old, with neuro symptoms for two and a half years. Since than I have been to two neuromuscular neurologist several times.
Prior these symptoms ( 9 years ago) I had very short therapy with accutane for acne (which is also chemoteraphy drug but is used in much smaller dosage when prescribed for acne) and now have problems with very slow skin healing, even a minor cut leaves nasty scar. Also since than, I have intermittent pain in hips and knees.
So, for two and a half y. I have complained for non-stop twitches (which never stop), which are appearing all over (even on my nose, tongue, back, belly) but neurologist never saw one on the exam and some changes in muscle bulk that started in the beginning and are very slowly progressing- thenar eminence, first dorsal int., brachioradialis, gastrocnemious and ext. digitorum brevis. It is all in my left body side. Also have problems with tongue feeling weird and sometimes feel fasciculations on it.Both neurologist said that there is nothing abnormal in these muscles I showed them. (But I am fairly certain that there is change in them since I'm quite an observer)
In the beginning on the neurological exam i presented with normal reflexes or normal on upper body and quite brisk in knee jerk, but no clonus. I have no plantar response (than and now still).
Yesterday I have been on another neuro exam and neuro wrote that I have quite brisk deep tendon reflex everywhere.
Neurologists never found any clinical weakness but I have percieved weakness that I feel when I play piano, or when I try to extend my toes.
It is harder for me to touch tip of my little finger with the tip of my thumb, whilist on my nondominant side there is no problem with doing that.
3 emgs were perfomed in the beggining, and yesterday.
Almost all muscles that i feel problems with have some chronic denervation from the beginning of testing 2.5 y ago ( high amplitude - up to 6 mV). Yesterday thenar muscle showed some insertional activity but it was in normal limits. From the begining neither neurologist found no fasciculations, PSW or fibrilations in any muscle tested.
All NCS studies were completly normal.
So it leaves me nowhere. I am concerned that I have chronic damage in those muscles, but there is no explanation for that. Am I right that it could not be any kind of neuropathy since there is no problems with NCS?
I know that some of my muscles are smaller in size although neurologists never think it is the case.
Few months ago I developed eye floaters in left eye, but I don't have it always. Also, this whole month I have excessive yawning for like 20-30 times in a day.
Please give me some ideas what could be the cause for chronic denervation, minor and slowly progressive atrophy and brisk tendon reflexes. Prior to neurologic symptoms I visited a rheumatologist and had blood tests for autoimmune conditions becouse of skin problems and joint pain but it was all clear. Also my mineral status till today is normal.
Please advise me!
I'm new to this forum as a member, but have reading you for a while and know enough to be really scared. I am female of 32 years old, with neuro symptoms for two and a half years. Since than I have been to two neuromuscular neurologist several times.
Prior these symptoms ( 9 years ago) I had very short therapy with accutane for acne (which is also chemoteraphy drug but is used in much smaller dosage when prescribed for acne) and now have problems with very slow skin healing, even a minor cut leaves nasty scar. Also since than, I have intermittent pain in hips and knees.
So, for two and a half y. I have complained for non-stop twitches (which never stop), which are appearing all over (even on my nose, tongue, back, belly) but neurologist never saw one on the exam and some changes in muscle bulk that started in the beginning and are very slowly progressing- thenar eminence, first dorsal int., brachioradialis, gastrocnemious and ext. digitorum brevis. It is all in my left body side. Also have problems with tongue feeling weird and sometimes feel fasciculations on it.Both neurologist said that there is nothing abnormal in these muscles I showed them. (But I am fairly certain that there is change in them since I'm quite an observer)
In the beginning on the neurological exam i presented with normal reflexes or normal on upper body and quite brisk in knee jerk, but no clonus. I have no plantar response (than and now still).
Yesterday I have been on another neuro exam and neuro wrote that I have quite brisk deep tendon reflex everywhere.
Neurologists never found any clinical weakness but I have percieved weakness that I feel when I play piano, or when I try to extend my toes.
It is harder for me to touch tip of my little finger with the tip of my thumb, whilist on my nondominant side there is no problem with doing that.
3 emgs were perfomed in the beggining, and yesterday.
Almost all muscles that i feel problems with have some chronic denervation from the beginning of testing 2.5 y ago ( high amplitude - up to 6 mV). Yesterday thenar muscle showed some insertional activity but it was in normal limits. From the begining neither neurologist found no fasciculations, PSW or fibrilations in any muscle tested.
All NCS studies were completly normal.
So it leaves me nowhere. I am concerned that I have chronic damage in those muscles, but there is no explanation for that. Am I right that it could not be any kind of neuropathy since there is no problems with NCS?
I know that some of my muscles are smaller in size although neurologists never think it is the case.
Few months ago I developed eye floaters in left eye, but I don't have it always. Also, this whole month I have excessive yawning for like 20-30 times in a day.
Please give me some ideas what could be the cause for chronic denervation, minor and slowly progressive atrophy and brisk tendon reflexes. Prior to neurologic symptoms I visited a rheumatologist and had blood tests for autoimmune conditions becouse of skin problems and joint pain but it was all clear. Also my mineral status till today is normal.
Please advise me!