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Shane the Pain

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Dear ALS family and friends,

A guy I know lives up in Long Beach CA area is taking this Pramipexole 22.5ml twice a day and he can't talk so good and his wife is his primary caregiver and doesn't have alot of time for fool questions from me...

So I was wondering if any of you brainiacs knows about this drug ?
 

Alyoop

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It's a dopamine agonist for the treatment of Parkinsons disease. I think there has been some talk that it may work in ALS, but no evidence that the theory is in anyway fact. Others may know more?
 

trfogey

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The Dexi trials that a lot of folks at PLM and a few here are involved in is actually dexipramipexole, a chemical cousin of pramipexole. Dexi doesn't have the dopamine affecting properties of pramipexole.

The best place to get more detailed information on that is probably the ALS TDI forum.
 

Alyoop

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Knew I had heard of it! :)
 

hjlindley

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Dec 1, 2011
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I asked my ALS neuro and the bottom line is the slight chemical differences keep it form being effective in safe doses.
 
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