nightowl
Member
- Joined
- Aug 19, 2017
- Messages
- 22
- Reason
- Loved one DX
- Diagnosis
- 11/2016
- Country
- US
- State
- Texas
- City
- Houston
Good Evening,
I ended up researching due to my own problems that I encountered recently. Long story; short
There may be a correlation between NSAIDs and muscle atrophy.
Link Here:
This is a study from 2004 which analyzed the effects of prostaglandin inhibitors on muscles, studied on rats. They saw that muscles that sustained injuries while on COX2 inhibitors/Prostaglandin inhibitors had a delayed regenerative effect when compared to those that did not have these medications.
I dont propose anything, but it may be possible that long use of these specific medications can cause long term damage. A theory, i suppose.
How i got to this:
My father has ALS, been sick for 5 years plus. Sporadic ALS.
I recently suffered a bulging L5 disk injury while at work and was prescribed Meloxicam. From my knowledge this medication was just like a "Tylenol/Advil" so I didnt think much about it. I took it for 1 week completely and by the second week I started noticing weird muscle twitches all around my body. Obviously, from my personal experience I thought the worst.
Reasons for twitching: high caffeine, stress, anxiety, no sleep, dehydration, etc. I live with all of those on the daily.
The day i stopped taking it, twitches were constant and had very bad sleep then i developed more anxiety, muscle pain, over the next days i began to feel a burning sensation; neuropathy with pins and needles all around my body. Over the next days i have had less twitching, neuropathy still present and a feeling of soreness as if i had been working out a lot.
My research for these symptoms had led me to this area.
Im not the best at medicine but I do have 10+ years of experience/knowledge in the medical field.
I ended up researching due to my own problems that I encountered recently. Long story; short
There may be a correlation between NSAIDs and muscle atrophy.
Link Here:
The COX-2 pathway is essential during early stages of skeletal muscle regeneration | American Journal of Physiology-Cell Physiology
Skeletal muscle regeneration comprises several overlapping cellular processes, including inflammation and myogenesis. Prostaglandins (PGs) may regulate muscle regeneration, because they modulate inflammation and are involved in various stages of myogenesis in vitro. PG synthesis is catalyzed by...
journals.physiology.org
This is a study from 2004 which analyzed the effects of prostaglandin inhibitors on muscles, studied on rats. They saw that muscles that sustained injuries while on COX2 inhibitors/Prostaglandin inhibitors had a delayed regenerative effect when compared to those that did not have these medications.
I dont propose anything, but it may be possible that long use of these specific medications can cause long term damage. A theory, i suppose.
How i got to this:
My father has ALS, been sick for 5 years plus. Sporadic ALS.
I recently suffered a bulging L5 disk injury while at work and was prescribed Meloxicam. From my knowledge this medication was just like a "Tylenol/Advil" so I didnt think much about it. I took it for 1 week completely and by the second week I started noticing weird muscle twitches all around my body. Obviously, from my personal experience I thought the worst.
Reasons for twitching: high caffeine, stress, anxiety, no sleep, dehydration, etc. I live with all of those on the daily.
The day i stopped taking it, twitches were constant and had very bad sleep then i developed more anxiety, muscle pain, over the next days i began to feel a burning sensation; neuropathy with pins and needles all around my body. Over the next days i have had less twitching, neuropathy still present and a feeling of soreness as if i had been working out a lot.
My research for these symptoms had led me to this area.
Im not the best at medicine but I do have 10+ years of experience/knowledge in the medical field.