It seems like no one knows for sure if they have PLS. It has definitely been interesting getting perspective from both people diagnosed with it and also family members dealing with it. Apparently my Dad is not ready to get onto this forum himself, but my Mom has been showing him several of our posts. I really think he is starting to turn the corner from a state of mind standpoint after reading our thoughts and yours. What I've really taken from this forum is that it is a good place to discuss all of the tests and guesses that are made at what the ailment is. My Dad recently had a spinal tap that came back normal as EVERY other test has. I guess I just can't understand how any diagnosis can be made from a bunch of NORMAL tests! If PLS is a disease that attacks your upper neurons or whatever they are called, why can't there be a test for that?