Could anyone help me? I have ulcerative colitis and in July 2005 I had a flare up and then in Sept 2005 I developed this pressure in the back of my head and neck. I was prescibed prednisone for my colitis and my colitis went into remission but my head pressure remained and felt better when I wore a hat. for the last 10-12 months my head pressure and colitis came back and I started experiencing twitches in my calf and I was on prednisone again but losing weight. I've had 2 EMG's last one in FEb 2009 and both came back normal. My head pressure is worse and my fingers are sore and I've lost muscle tone in my arms and legs plus my neck is stiff and grinds when I move it. All my muscles in my body are sore and my mouth is extremely dry. I can walk even though I have numbness in my legs. My concern is my colitis is active and the doctor wants to try Remicade injections to put my colitis back into remission. Even though I'm bleeding a lot from my rectum my head bothers me more and I wake up each day with numbness in my limbs mostly my right hand. I recently started to have a sore throat without having a cold. Nothing seems to relieve my head pressure, I've tried everything> My muscles have this burning feeling which I havn't experienced before> Could anyone shed any light if this could be ALS