:-D
About the research which has been nicknamed "brain cleaner".
Maybe I have posted my earlier posts in the wrong category and as new member, have only now noticed this “research news” category.
Here is all that I have learned so far in the past 3 weeks:
This work is aiming to create conditions in the body that would cause “Pyruvate” a simple and cheap product available over the counter, under the right conditions and with the patented technology, to act as a “Glutamate scavenger”, i.e. Something that our body may anyway be doing but on a very small scale. Too small a scale for what PALS need.
We all know very well that drugs like Relutek / Riluzole are designed to help us by temporarily blocking the glutamate's toxic action with the drugs inside the brain. In contrast, “Brain cleaner” = “Glutamate scavenger” is intended to clear the chemical away from the brain back and through the blood, where it can't do harm anymore."
Anyone reading Aall the info that is available on the internet regarding on the “Brain cleaner” = “Glutamate scavenger” you could be made to feel very confident with its forthcoming realization into our arsenal in our fight against ALS and other neurological damage. This is because it is reported that “This method may soon be entering clinical Human” Sounds great !
In reading the news flashes on the net one would also read that “The US FDA has assured the company of a fast track to approval”. This is true and sounds real and great – some real hope for us all, right?
Please be aware that unless we all the PALS community act in our own interest, research like this one will never see the light of day, despite its potential and the great promise that it shows.
Unfortunately, once again politics and probably more so profits$$$$ ( or lack of) are standing in the way of this work progressing further.
Let me explain, It turns out that the glutamate scavenging patented technology is so brilliant, that it uses a simple and cheap ingredient that is and readily available over the counter.
So you may ask, what’s the problem?
It follows that the human trails may show that because the ingredient ( if I can call it this) is so cheap that it may not return mega profits in the usual manner as may be generally expected in by BIG PHARMA, and Big Pharma will not invest at this time.
So as it stands now the researchers are stuck waiting for funds to support the first human trail. A simple and harmless trial with big promise.
Can any one think of a better place then this for the ALS association to direct extra attention which will allow some flow of funds?
Al, you have accumulated so much knowledge and experience in this arena, please give me your opinion in regard to what power of influence our community and association may have to aid with what seems to be something so promising.
http://www.eurekalert.org/pub_releases/2007-01/acft-bc011707.php
http://www.neuroskills.com/pr-cleaner.shtml
http://www.innovations-report.com/html/reports/life_sciences/report-77237.html
and another member
fairborn, oh US
Join Date: 2008
has posted:
The study is published in a peer-reviewed journal. Here is the citation:
Zlotnik et al. Brain neuroprotection by scavenging blood glutamate. Experimental Neurology. 203(1): 213 - 220, 2007.
About the research which has been nicknamed "brain cleaner".
Maybe I have posted my earlier posts in the wrong category and as new member, have only now noticed this “research news” category.
Here is all that I have learned so far in the past 3 weeks:
This work is aiming to create conditions in the body that would cause “Pyruvate” a simple and cheap product available over the counter, under the right conditions and with the patented technology, to act as a “Glutamate scavenger”, i.e. Something that our body may anyway be doing but on a very small scale. Too small a scale for what PALS need.
We all know very well that drugs like Relutek / Riluzole are designed to help us by temporarily blocking the glutamate's toxic action with the drugs inside the brain. In contrast, “Brain cleaner” = “Glutamate scavenger” is intended to clear the chemical away from the brain back and through the blood, where it can't do harm anymore."
Anyone reading Aall the info that is available on the internet regarding on the “Brain cleaner” = “Glutamate scavenger” you could be made to feel very confident with its forthcoming realization into our arsenal in our fight against ALS and other neurological damage. This is because it is reported that “This method may soon be entering clinical Human” Sounds great !
In reading the news flashes on the net one would also read that “The US FDA has assured the company of a fast track to approval”. This is true and sounds real and great – some real hope for us all, right?
Please be aware that unless we all the PALS community act in our own interest, research like this one will never see the light of day, despite its potential and the great promise that it shows.
Unfortunately, once again politics and probably more so profits$$$$ ( or lack of) are standing in the way of this work progressing further.
Let me explain, It turns out that the glutamate scavenging patented technology is so brilliant, that it uses a simple and cheap ingredient that is and readily available over the counter.
So you may ask, what’s the problem?
It follows that the human trails may show that because the ingredient ( if I can call it this) is so cheap that it may not return mega profits in the usual manner as may be generally expected in by BIG PHARMA, and Big Pharma will not invest at this time.
So as it stands now the researchers are stuck waiting for funds to support the first human trail. A simple and harmless trial with big promise.
Can any one think of a better place then this for the ALS association to direct extra attention which will allow some flow of funds?
Al, you have accumulated so much knowledge and experience in this arena, please give me your opinion in regard to what power of influence our community and association may have to aid with what seems to be something so promising.
http://www.eurekalert.org/pub_releases/2007-01/acft-bc011707.php
http://www.neuroskills.com/pr-cleaner.shtml
http://www.innovations-report.com/html/reports/life_sciences/report-77237.html
and another member
fairborn, oh US
Join Date: 2008
has posted:
The study is published in a peer-reviewed journal. Here is the citation:
Zlotnik et al. Brain neuroprotection by scavenging blood glutamate. Experimental Neurology. 203(1): 213 - 220, 2007.
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