I've got a lot of twitching, but NOT in the face. I do get the lump-in-the-throat feeling, stiffness in the neck and weakness in the neck--now I understand why Stephen Hawking goes around with his head to one side! Gosh I'd like to put on a neck brace sometimes, but i'm afraid artificial support would make the muscles weaken faster. My hands have been atrophying for almost three years, but I've kept up a LOT of bicycling, and so far my legs are still strong. No way to know for sure if the exercise is what has kept my legs from atrophying, but it apparently hasn't hurt.