I am still new to this so alot of questions I cannot answer. Even tho I have had symptoms for over two years I did not seek medical attention until six months ago. On my many trips to the emergency room for falls, the doctors there said it was nothing. I fell while at work about 6 months ago, I could not get my arms out in front of me to break my fall so needless to say I really hurt myself. The doctor at this time accused me of being drunk because of my slurred speach and constant laughing. The whole left side of my face and head was bloody and bruised. The funniest thing about his remark about being drunk is that I do not drink at all ever. So when he said that of course I thought It was the funniest thing I had ever heard and that set me off on another laughing spell, I started choking couldn't catch my breath because I couldn't stop laughing.
However he did recommend I see a neurologist. I did see my first neurologist who was a real idiot. I Finally came across a good internal medicine doctor who knew right away I had a serious neurological condtion. He then reffered me to a neurologist at the university of washington. There I seen two neurologists who did a number of blood tests and different neurological exams, EMG/NCV prior to receiving any test results they told me I probably had PLS possible ALS. All the test results came back. They called me back in to confirm to me that I had PLS. But still have to go back in december for 3 month checkup. They did tell me some people go on to develop ALS.
As for yor question about twitching, the answer is yes and it is constant, mostly in my legs but it is over my entire body. Cramps all the time. shortness of breath, sometimes. My voice is almost gone........:x The only people who can understand me is my daughters and my mom. My legs are very weak as well as my left hand. Muscle wasting, not that I have noticed. I think for me I came across some really good doctors after having been to so many licence to practice out of a cracker jack box.