DrDark
Active member
- Joined
- Mar 1, 2019
- Messages
- 30
- Reason
- PALS
- Diagnosis
- 09/2015
- Country
- US
- State
- Virginia
- City
- pennsyltucky
My understanding of Neudexta is that the dextromethorphan is what helps PBA. If dextromethorphan is the active ingredient in Neudexta, and quinidine is only there to slow the metabolism of the DM, shouldn't any sustained release form of DM be helpful? Quinidine interacts with other meds that can increase QT interval on ecg, and therefore increase risk of fatal arrhythmia. Also, the branded combination can be prohibitively expensive and present access obstacles for some pALS, as I have read in these forums.
Are there any users here with a pharmacology background who can set me straight? My understanding of the mechanism may be flawed. I plan on asking my neurologist when I see him in a few weeks, but I wonder if anyone here has any insight.
Has anyone tried an alternative like Delsym?
Are there any users here with a pharmacology background who can set me straight? My understanding of the mechanism may be flawed. I plan on asking my neurologist when I see him in a few weeks, but I wonder if anyone here has any insight.
Has anyone tried an alternative like Delsym?