i have been doing supplemens since day one feb/2010. i do a test every 2-3 months to detetrmine what my body needs carefully interputed by herbalist. she frequently passes on some saying continue what you are doing. when an organ problem is corrected i discontinue the supplement when supply runs out. at this point i do ten, counting vitimins, supplements, co-q10, beta-careton, creatine and aloe vera. still walk, talk, eat and breat on my own, but limbs are weak. fvc 89-92, bulbar region still good. if you decide to commit to supplements its for the long haul. it does not stop or reverse als. the best it can do is make you feel good, make your immune system healthy to fight body aliments, and i truely believe it has kept my body progressing slowly