VEGF all of a sudden everyone shuts up
ohhhh isnt it ironic that when i ask a question about a therapy not to do with stem cells everyone suddenlyl goes silent? I guess my previous posting is true and you are all interested in putting down people but not having meaningful discussionl.
Well here is what I found about VEGF if anyone cares
Its being developed under the name sNN0029 by a company called Neuronova (
www.neuronova.com) and below are some papers
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.
Storkebaum E, Lambrechts D, Dewerchin M, Moreno-Murciano MP, Appelmans S, Oh H, Van Damme P, Rutten B, Man WY, De Mol M, Wyns S, Manka D, Vermeulen K, Van Den Bosch L, Mertens N, Schmitz C, Robberecht W, Conway EM, Collen D, Moons L, Carmeliet P
Nature Neurosci, 2005 Jan;8(1):85-92
Commentary to paper above: VEGF: multitasking in ALS.
Vande Velde C, Cleveland DW
Nat Neurosci. 2005 Jan;8(1):5-7
Blood vessels and nerves: common signals, pathways and diseases.
P Carmeliet
Nature Rev Genet, 2003 Sep;4(9):710-20
Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis.
Brockington A, Wharton SB, Fernando M, Gelsthorpe CH, Baxter L, Ince PG, Lewis CE, Shaw PJ
J Neuropathol Exp Neurol, 2006 Jan;65(1):26-36
Vascular endothelial growth factor in amyotrophic lateral sclerosis and other neurodegenerative diseases.
Bogaert E, Damme PV, Van Den Bosch L, Robberecht W
Muscle Nerve, 2006 Oct;34(4):391-405
Paul.nagourney said:
Dear Lorie,
I apologize sincerely to you and everyone else i may have offended. This is a terrible disease and we all have to try to learn more...and KEEP AWAY FROM SCAMS.
The Cellmedicine folks impressed me but so what. lets finish with that topic.
I want to ask. Does anyone know of VEGF therapy for ALS? There was some rumours about this being tried in Europe.
Again, for the Cellmedicine comments...sorry...sincerely didnt want to get people arguing or hating me. I really enjoy this forum and learn alot from reading the comments posted on it.