StarryNight
New member
- Joined
- Feb 26, 2020
- Messages
- 1
- Reason
- Learn about ALS
- Diagnosis
- 00/0000
- Country
- CA
- State
- QC
- City
- Montreal
Hello,
I don't know very much about ALS but I am worried as my husband seems to have a family history. When I dug deeper into this family history, it seemed to me as though some things don't add up.
My husband's youngest paternal uncle passed away this year from ALS. He was the youngest of about 8 siblings, male and female. He was the only affected one. These siblings came from unaffected parents. However, these siblings have 2 or 3 paternal aunts/uncles who apparently also had ALS. I find it weird that the gene seemed to skip down to the nephew without affecting the parent. Furthermore, none of the affected great aunts/uncles passed ALS on to their offspring.
I wondered if the gaps could be explained by FTD possibly? My husband's father does have a strange personality, occasional inappropriate behaviour. Nothing crazy, but a bit odd. I wondered if he had FTD. My husband reports that his dad has always been this way, since he was a kid. (Husband is now 31, father is in late 50s/early 60s).
I'm confused. I feel as though my uncle's husband possibly had sporadic ALS, and maybe the great aunts/uncles had other neurological issues (such as strokes?) that the family felt was similiar and so decided it was the same diagnosis.
I'm really worried. I do understand that genetic testing is the way to go, but my husband doesn't want to go down that route. Hope you guys can help me find some reassurance.
I don't know very much about ALS but I am worried as my husband seems to have a family history. When I dug deeper into this family history, it seemed to me as though some things don't add up.
My husband's youngest paternal uncle passed away this year from ALS. He was the youngest of about 8 siblings, male and female. He was the only affected one. These siblings came from unaffected parents. However, these siblings have 2 or 3 paternal aunts/uncles who apparently also had ALS. I find it weird that the gene seemed to skip down to the nephew without affecting the parent. Furthermore, none of the affected great aunts/uncles passed ALS on to their offspring.
I wondered if the gaps could be explained by FTD possibly? My husband's father does have a strange personality, occasional inappropriate behaviour. Nothing crazy, but a bit odd. I wondered if he had FTD. My husband reports that his dad has always been this way, since he was a kid. (Husband is now 31, father is in late 50s/early 60s).
I'm confused. I feel as though my uncle's husband possibly had sporadic ALS, and maybe the great aunts/uncles had other neurological issues (such as strokes?) that the family felt was similiar and so decided it was the same diagnosis.
I'm really worried. I do understand that genetic testing is the way to go, but my husband doesn't want to go down that route. Hope you guys can help me find some reassurance.