These are a few of the studies which have linked iron to ALS.
"The SWI patterns observed in this study suggest that widespread alterations due to iron disturbances occur in patients with ALS and correlate with disease severity."
"quantitative evidence for increased iron deposition in closely localized regions along the CST in ALS patients"
"Iron-mediated oxidative stress plays a pivotal role in the pathogenesis of amyotrophic lateral sclerosis"
"ALS patients have altered iron metabolism"
"Increased iron level in motor cortex of amyotrophic lateral sclerosis patients"
"ALS patients may have increased iron storage, as measured by increased serum ferritin and TSC"
"Iron chelation therapy may have the potential for the prevention and treatment of ALS"
"Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis"
"SOD1-dependent mechanism for iron to manifest its cellular toxicity"
"Brain iron MRI: A biomarker for amyotrophic lateral sclerosis"
"Inappropriately chelated iron in the cerebrospinal fluid of amyotrophic lateral sclerosis patients"
"may respond to therapies that reduce iron intake or increase iron elimination"
"Superficial siderosis of the central nervous system: secondary progression despite successful surgical treatment, mimicking amyotrophic lateral sclerosis"
"iron-chelating drugs possessing neuroprotective/neuritogenic activities may offer future therapeutic possibilities for motor neurodegenerative diseases."
"Frontotemporal Dementia-amyotrophic Lateral Sclerosis Complex is Simulated by Neurodegeneration With Brain Iron Accumulation"
"Dysregulation of iron metabolism in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis"
"Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients"
“Iron accumulation and dysregulation of iron transport and storage has been found to be associated with many other neurodegenerative conditions, such as Parkinson’s disease, Huntington’s disease (HD), multiple sclerosis and Amyotrophic Lateral Sclerosis"
"Iron Metabolism Disturbance in a French Cohort of ALS Patients"
"novel multimodal iron-chelating drugs possessing neuroprotective/neuritogenic activities may offer future therapeutic possibilities for motor neurodegenerative diseases"
"studies investigating high nutrition diets and iron chelation for the treatment of ALS are warranted"
"neurodegeneration with brain iron accumulation mimicking juvenile amyotrophic lateral sclerosis"
"Iron in Frontotemporal Lobar Degeneration"
"iron accumulation, oxidative damage and chronic inflammation as common pathognomonic signs of a number of neurodegenerative diseases that includes Alzheimer's disease, Huntington disease, amyotrophic lateral sclerosis, Friedrich's ataxia and Parkinson's disease"
"High levels of iron have been found in the brains of people with neurodegenerative diseases like Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis (Lou Gehrig’s disease)"
"Motor cortex hypointensity on 3T MRI FLAIR images in ALS is due to increased iron accumulation by microglia"
"Three new drugs to treat and perhaps prevent neurodegenerative diseases including Alzheimer's, Parkinson's and ALS recently received patents. The trio of drugs mop up excess iron before it can trigger a "brain rust" chemical reaction, a hallmark of many neurodegenerative diseases."
"Iron has been shown to accumulates at site where neurons degenerate in neurodegenerative diseases of Parkinson's disease, Alzheimer's disease, Huntington disease, amyotrophic lateral sclerosis and Friedreich ataxia"