GaborBP
Member
- Joined
- Sep 11, 2017
- Messages
- 10
- Reason
- Lost a loved one
- Country
- HUN
- State
- Budapest
- City
- Budapest
Hi,
I'm a realtively old member of the DIHALS forum, so I'll try to be as straightforward as possible to recap the basics:
My father passed away from PBP at the of 56. No other family member had MND, and he encountered both head trauma and large amounts of diesel exhaust.
I've had widespread fasciculations in the last 3 years, and received a dirty EMG in September '17, including in the dreaded thoracic paraspinals. The EMG doc straight up declared that "what if I told you that you had the same disease as your father? You wouldn't be able to do anything, would you?" However, my primary neuro (his boss) doesn't believe it's ALS.
In the last 6 months, I've been experiencing swallowing problems, which are slowly getting better.
The interesting part is that it was revealed that my B12 level stands at 77, while my iron level was first off the charts, then dropped to the lower threshold in 2 weeks time. What's more unnerving is that is have slightly low ceruloplasmin with high free copper - which is an ALS biomarker.
My question is: is it possible for a predominantly UMN disease like B12 deficieny to mimic a full blown LMN dominant ALS? I've never heard of it attacking anything else than the legs. Also, what about the iron? I'm aware that ferritin is high in PALS, but this is serum iron.
I'm a realtively old member of the DIHALS forum, so I'll try to be as straightforward as possible to recap the basics:
My father passed away from PBP at the of 56. No other family member had MND, and he encountered both head trauma and large amounts of diesel exhaust.
I've had widespread fasciculations in the last 3 years, and received a dirty EMG in September '17, including in the dreaded thoracic paraspinals. The EMG doc straight up declared that "what if I told you that you had the same disease as your father? You wouldn't be able to do anything, would you?" However, my primary neuro (his boss) doesn't believe it's ALS.
In the last 6 months, I've been experiencing swallowing problems, which are slowly getting better.
The interesting part is that it was revealed that my B12 level stands at 77, while my iron level was first off the charts, then dropped to the lower threshold in 2 weeks time. What's more unnerving is that is have slightly low ceruloplasmin with high free copper - which is an ALS biomarker.
My question is: is it possible for a predominantly UMN disease like B12 deficieny to mimic a full blown LMN dominant ALS? I've never heard of it attacking anything else than the legs. Also, what about the iron? I'm aware that ferritin is high in PALS, but this is serum iron.