Hi. I posted on here last week how I began to have twitching everywhere and was concerned about ALS. I had my neuro visit yesterday and he highly doubted it. He checked all my reflexes and all was normal. He didn't really do a full on exam because I had seen him 3 weeks prior with tingling issues and he did it then. Anyways, I had mentioned to him that I had been trying to exercise more, but the last few days, my left knee has kind of given out on me while walking. He seemed no not even flinch. I thought that knee buckling was a classic sign of weakness and it has happened 3 times in 3 days. There is no pain involved. For instance, last night I went jogging with my daughter in the jogger stroller and right after I stopped, my left knee buckled. I didn't fall, but I was definitely aware of it happening. Anyways, I told him I wanted an EMG and he said that he thought I was chasing up the wrong tree, but that if it would put my mind at ease, he'd order one. He told me that he was pretty sure all would come back normal. He did not that my left leg was 1 1/2 cm. smaller than my left leg, but told me it had probably always been this way. I know my neuro is not concerned, but I know from talking to him that a major reason for this is because I'm only 25 and he said it is so rare in my age group. I do believe what he's saying, however, from searching around on this forum, there are some people whose only symptom at first was knee buckling. Unfortunately, I can't get in for my EMG for 2 more weeks. Do you think my knee giving out is clinical weakness? On a side note, my twitching has greatly subsided. I barely had any twitching at all yesterday. Thank you for your time.