I experienced an increase in wakefulness at night while on SSRIs (sertraline and celexa). I also started getting increased myoclonic jerks and auditory hallucinations when I finally did fall into a half sleep. SSRIs were definitely NOT for me! As it was something the doctor recommended to help me sleep, it was a gigantic failure.
I am currently trialing amitriptyline at a very low dose to see if that helps me sleep. So far so good.
I think it depends on why you're taking antidepressants. If it's for sleep, a vastly lower dose can be more effective than the so called "therapeutic" dose that is recommended by the manufacturer.
Note- I am upper motor MND, and my spasticity and reflexes were affected for sure. It may be different for those with LMN predominant or ALS.