I just wanted to note in case somebody reviews this thread. Another possibility has dawned on me. I had a serious systemic reaction to Statins a year ago and suffer from high Cholesterol. My cardiologist prescribed a new drug called Repatha. It is a 1x a month 9 min intraveneous leg infusion drug to lower cholesterol that claimed to have little reported muscular reaction. I took the drug on Nov 7, and Dec 7th. My problems started soon after my first dose. I believe this is possibly my cause of leg weakness, twitches, hyper relexes, and spasticity. I didnt take my Jan dosage and it seems my issues are fading this week. IE much less spasticity, twitching ended, weakness still prevalent but feeling it may be improving a little. I learned that the drug companies and the FDA have misinformed the public about the efficacy and saftety of cholesterol drugs. When big pharma does a study, they first test participants for 90 days to determine if they are allergic. If they have a reaction (30% believe they do) they do not include them in the study or follow them in any manner,, nor do they report the hospitializations or deaths of these people in any manner. The protocol is not only flawed but outright dangerous to the public. What;s more, big pharma never shares the raw data with the medical community to confirm its accuracy. The efficacy of these drugs even with the biased basis has not shown in any study since 2006 any life expectancy improvement. It very well could be a cause of nuero muscular disease including ALS and other life threatening diseases. I will never take another cholesterol drug as long as I live.