Hi! It does seem strange that there are improvements, but one thing we discovered through some research is that in the early stages, that the body will try to find ways around damaged areas. My partner, Michel, started taking brufen early on, and not for pain, which all the doctors thought he was taking it for, but for inflammation. He found when he took this that he felt he could walk better. So, my thought may be that it may not be an actual reversal or improvement, but the body working around affected areas. However, as the disease progresses, this becomes less and less possible. Also, my partner underwent every test possible, and these all came back negative. His neurologist said he could be in the small percentage that show a negative result but actually have MND. At one stage he was diagnosed as having auto-immune disease which made us jump for joy because he could have 4 months of treatment with IVIG and get better. I knew before he started the treatment, that it was probably MND. We went out to dinner one evening before Christmas 2011, and he started slurring his words. He sounded drunk and we had not even had a drink. That was my sign! Also, as his third neurologist reminded us when he confirmed ALS, it is all about the process of eliminating everything else. I hope it is not your father's case. Graham