Nexium is the most expensive(that I know) but it is CURATIVE. Be patient because it isn't usually immediate. After a few weeks, it's cured more people than I can count with extreme reflux issues, and other problems. It's a winner.You are going to be FINE!!!!Of course, it always helps to go to bed on as empty as possible stomach, because sleep is restorative, and digestion is the hardest work your body does.It is beneficial for your overall health not to mix the two.Let me know how it goes.