Hi Skipper66. So far Tom is doing fine, he has been on daily shots for two weeks now. No side effects. He sleeps fine, he did think maybe he was taking longer naps but I don't think so. Oh how I hope this slows things down even more. I am so grateful that he can still do so much. I googled what Acthar costs on the open market. $28,000 PER VIAL! And we have three in our refrigerator! We discussed this with our study manager, she said it was true, they don't like to mention it. Sure glad he's on it for FREE!