My husband has been on it since December 9, 2022. We were originally told he had to be within 18 months of his diagnosis to qualify. He was diagnosed on November 2, 2020. He has experienced diarrhea...but that is it. He is also taking Radicava and Riluzole. It is impossible to measure if anything is working....seems he has progressed in the disease in the last couple of months. 