Clinical Trials

Our clinic trial news comes directly from the U.S. National Institutes of Health.   If you have additional trial information please post it to our website or let us know by email.

ALS Reversals - Lunasin Regimen

Condition:   ALS (Amyotrophic Lateral Sclerosis)
Interventions:   Drug: Lunasin Regimen;   Other: Historical control
Sponsor:   Richard Bedlack, M.D., Ph.D.
Active, not recruiting - verified February 2017

Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS)

Condition:   Amyotrophic Lateral Sclerosis
Interventions:   Device: PowerLung trainer;   Device: Micro Mouth Pressure Meter;   Procedure: Pulmonary Function Testing;   Procedure: Videofluoroscopic swallowing study;   Other: Swallowing Quality of Life Questionnaire;   Device: Iowa Oral Pressure Instrument;   Drug: Capsaicin
Sponsors:   University of Florida;   ALS Association
Recruiting - verified February 2017

Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocellular Carcinoma (HCC)

Conditions:   Fibrolamellar Hepatocellular Carcinoma;   Hepatocellular Carcinoma (Fibrolamellar Variant);   Hepatocellular Carcinoma
Interventions:   Procedure: living related donor partial liver transplantation;   Radiation: Total body irradiation;   Procedure: Bone marrow transplant from same donor;   Drug: Cyclophosphamide;   Drug: Mesna;   Drug: Filgrastim;   Drug: Tacrolimus;   Drug: mycophenolate mofetil;   Drug: Prednisone;   Drug: Antithymocyte globulin;   Drug: fludarabine

Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS

Condition:   C9ORF72 Amyotrophic Lateral Sclerosis (ALS)
Intervention:  
Sponsors:   Washington University School of Medicine;   Cedars-Sinai Medical Center;   UMC Utrecht;   Johns Hopkins University;   Sentara Health Care/Sentara Neurology Specialists;   Massachusetts General Hospital;   University of Massachusetts, Amherst;   Biogen;   ALS Association;   Columbia University
Recruiting - verified January 2017

Tongue Motor Recruitment During Exercise

Condition:   Healthy
Interventions:   Procedure: Electromyography;   Procedure: Maximum expiratory pressure;   Procedure: Videofluoroscopy;   Behavioral: Swallowing Tasks
Sponsor:   University of Florida
Completed - verified January 2017

Allo HSCT Using RIC for Hematological Diseases

Conditions:   Acute Myelogenous Leukemia;   Acute Lymphocytic Leukemia;   Chronic Myelogenous Leukemia;   Plasma Cell Leukemia;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma;   B-Cell Lymphoma;   Follicular Lymphoma;   Lymphoplasmacytic Lymphoma;   Mantle-Cell Lymphoma;   Prolymphocytic Leukemia;   Lymphoblastic Lymphoma;   Burkitt's Lymphoma;   Non-Hodgkin's Lymphoma;   Multiple Myeloma;   Myeloproliferative Syndromes;   Hematological Diseases

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