May 2013

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

Conditions:   GATA2;   Immunodeficiency;   MDS
Interventions:   Procedure: Allogeneic HSC;   Drug: Busulfan Test dose;   Drug: Fludarabine(Fludara, Berlex Laboratories);   Drug: Busulfan (Busulfex);   Drug: Cyclophosphamide(CTX, Cytoxan);   Procedure: Total Body Irradiation (TBI);   Drug: Equine Anti-Thymocyte Globulin
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified January 5, 2017

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Conditions:   Primary Renal Allograft Candidate;   Kidney Transplantation
Interventions:   Biological: Anti-thymocyte Globulin (Rabbit);   Biological: belatacept;   Drug: methylprednisolone;   Biological: basiliximab;   Drug: mycophenolate mofetil;   Drug: tacrolimus
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Clinical Trials in Organ Transplantation
Terminated - verified June 2016