EJTUNow
Member
- Joined
- Mar 25, 2013
- Messages
- 28
- Reason
- Learn about ALS
- Country
- US
- State
- North Carolina
- City
- Carteret
Iwould suggest to you that ALS TDI Seems to focus mainly on traditional drug therapy.
It might be that drug therapy will become yesterday's solution.
I was on Gilenya for over 3 months with no positive indication, I hope ALS TDI has rolling data reporting so that the trial can be terminated early based on breakthrough results that help patients, or signs of poor results. Remaining dollars might be reallocated for stem cell and gene therapy
in this article On ALSTDI website note that drug, or medicine is mentioned 4 times; stem cells And gene therapy 0 times!
The ABCs of ALS Therapies
More than 100 medicines have been tested as possible treatments for ALS. But only riluzole is FDA-approved: a drug that at best, moderately treats the disease.
A considerable obstacle toward developing more effective treatments for neurologic diseases including ALS is the blood brain and spinal cord barriers which in part, keep certain toxic substances circulating in the blood out of the central nervous system. These cellular-based barriers block potential medicines from getting into the brain and spinal cord. And, drug pumps called ABC transporters installed within these barriers kick drugs that sneak into ALS-ravaged nerves back out into the blood
The ABCs of ALS Therapies | ALS Therapy Development Institute
It might be that drug therapy will become yesterday's solution.
I was on Gilenya for over 3 months with no positive indication, I hope ALS TDI has rolling data reporting so that the trial can be terminated early based on breakthrough results that help patients, or signs of poor results. Remaining dollars might be reallocated for stem cell and gene therapy
in this article On ALSTDI website note that drug, or medicine is mentioned 4 times; stem cells And gene therapy 0 times!
The ABCs of ALS Therapies
More than 100 medicines have been tested as possible treatments for ALS. But only riluzole is FDA-approved: a drug that at best, moderately treats the disease.
A considerable obstacle toward developing more effective treatments for neurologic diseases including ALS is the blood brain and spinal cord barriers which in part, keep certain toxic substances circulating in the blood out of the central nervous system. These cellular-based barriers block potential medicines from getting into the brain and spinal cord. And, drug pumps called ABC transporters installed within these barriers kick drugs that sneak into ALS-ravaged nerves back out into the blood
The ABCs of ALS Therapies | ALS Therapy Development Institute