My husband's symptoms are primarily in his legs and to a lesser degree his upper body and right hand.
He noticed first just that it was 'harder' to do things he's always done. First, he couldn't do his push ups as easily, then he couldn't do as many...With his legs, they literally feel fatigued to the point that he needs to sit down if he's up on them for more than 15 minutes. Now, noticing one leg (his normally dominant/stronger leg) is not as strong, and his gait is a bit more...stiff, sluggish, awkward.
We seem to constantly be waiting to see what "the next symptom or change" will be. ugghhh