Multiple Sclerosis Drug to be tested for ALS

[apollick]

February 15, 2012 - Received this last evening

ALS TDI to Test Multiple
Sclerosis Drug in ALS
The MDA-supported ALS Therapy Development Institute (ALS-TDI) plans to launch a phase 2 clinical trial of TDI 132, a compound that modulates the immune system

Article Highlights:
• The nonprofit biotech ALS Therapy Development Institute plans to launch a phase 2 trial to determine the safety and tolerability of TDI 132 — also known as fingolimod — in ALS.
• Fingolimod (brand name Gilenya) is approved by the U.S. Food and Drug Administration for the treatment of multiple sclerosis. In humans, Gilenya inhibits certain immune system cells from entering the central nervous system, where they can result in damage to motor neurons.
• ALS TDI reports that mice treated with TDI 132 showed positive outcomes on several disease measures.
To learn more, read the full ALS News Online article.
als.mda.org
Scott Wiebe
National Director — Outreach Services & ALS Division



World Leader in ALS Research and Services

[odiva]

I have often wondered why they haven't thrown the other neuro-muscular drugs at ALS. They still are not sure what causes ALS. Come on..we are willing to be human guinea pigs, we have nothing to lose and everything to gain. At least I speak for myself.

[HelenL]

Here's the link:

ALS TDI to Test Multiple Sclerosis Drug in ALS | MDA/ALS Newsmagazine

[Alyoop]

They should test the study drug that I have been working, with on an ms study, and trial it for ALS as well. It's had very positive results in ms and is with the FDA waiting approval. Doctors at ms conferences have been talking about looking into it's use with ALS. Fingers crossed they will take it into studies with ALS.