My wife has used RCH4 for the past 41 months. There is no doubt, when looking at her ALSFRS chart, that is has dramatically slowed the progression. If we extrapolate her decline prior to RCH4, she should have died about a year ago. As far as those who claim it is a placebo effect, well, that usually lasts days or weeks, not years. I have never been able to understand the critics. Shouldn't something that actually works be promoted in the ALS community? Instead, it has been accused of being a scam, to which I have asked, releatedly, if we have never been asked to pay a single penny for a treatment, and they have never promised any effectivity, how can it be a scam? Nobody has yet wanted to answer that question. To those who ask, how can you inject that when you don't know what it is, I say, of course we had concerns initially, but it's a TERMINAL disease with no treatment options. What other choice does one have? I do agree that it is a shame that so few have access. We were just lucky when we stumbled across them. If the ALS community would embrace RCH4 and try to bring it to market, which requires hundreds of thousands, and probably millions, of dollars, instead of shouting down something THEY KNOW NOTHING ABOUT, then perhaps more would have access.