Ash12345
New member
- Joined
- Jan 26, 2017
- Messages
- 9
- Reason
- DX MND
- Diagnosis
- 05/2016
- Country
- US
- State
- MA
- City
- Boston
Thanks Nikki,
I have been following all the gene blocking trials for sod1.
I myself is sod1 h47r (a very very rare variant). All the research is going on with sod1 G93A mutations. My concern is that if it works for sod1 G93A, will it work for other sod1 variants as well.
Thanks
Search for antisense therapy, biogen, gene silencing. Antisense is being used for SMA as I said. It is in hopeful looking trials for HD and SOD1
My neurologist has consistently said it represents the best hope for my family. In fact she says don’t worry about the kids and is optimistic for my currently asymptomatic cousins who are all older now than our youngest onset age
It makes sense to me that if our ALS is caused by a mutant gene blocking the function that causes the damage should be the answer[/QUOTE]
I have been following all the gene blocking trials for sod1.
I myself is sod1 h47r (a very very rare variant). All the research is going on with sod1 G93A mutations. My concern is that if it works for sod1 G93A, will it work for other sod1 variants as well.
Thanks
Search for antisense therapy, biogen, gene silencing. Antisense is being used for SMA as I said. It is in hopeful looking trials for HD and SOD1
My neurologist has consistently said it represents the best hope for my family. In fact she says don’t worry about the kids and is optimistic for my currently asymptomatic cousins who are all older now than our youngest onset age
It makes sense to me that if our ALS is caused by a mutant gene blocking the function that causes the damage should be the answer[/QUOTE]