Jennyf12345
New member
- Joined
- Oct 4, 2017
- Messages
- 1
- Reason
- Loved one DX
- Country
- US
- State
- MO
- City
- Saint Louis
My 55 yo husband has had neurological symptoms for a couple of years and was just told by a neurologist that ALS is "the front runner" in terms of his diagnosis. His grandmother died 30 years ago at 82 of what they were told was something "ALS-like". She was diagnosed in her late 70s. The generation in between (husband's mother) died of emphysema at 77 (heavy smoker). Of his mother's other siblings, one is still going at 90 and another died of unrelated causes. No other known cases in the family. From what I've read, it would be unusual for a fALS gene to skip a generation but not impossible due to penetrance variables, is that correct? I'm also gathering that it would also be unusual (but not impossible) for fALS to present in one person at 80 and another at 55? Has anyone had this happen in their family? His family is mostly of European (Italian) ancestry. We have three young children. Thanks to all of you who share information in this forum--it's a scary topic but this is a great resource.