Lena Lennartsson
Member
- Joined
- Oct 4, 2010
- Messages
- 10
- Reason
- Loved one DX
- Country
- SE
- State
- Västra Götaland
- City
- Göteborg
I have some queries about hereditary ALS. In this forum I've read that if a parent has ALS, the child has a 50 % risk of developing the desease. I know for a fact that this isn't always true. Some info seems to indicate that the 50 % risk of getting sick only applies for people with SOD1, is that true? And that you otherwise have a 50 % risk of inheriting the affected gene, but that that doesn't mean you'll get sick.
My mother and one of her brothers have / have had ALS och their uncle (mother's brother) probably had it too (diagnosed as MS 40 years ago). My grandmother had 3 siblings. As mentioned, her brother seems to have had ALS and she herself seems to have been a carrier. My mother had 9 brothers and sisters, and is the youngest one of the bunch. Several of the others are well over 80 years old and healthy. My grandmother was 83 when she died.
Does this mean that we don't have the SOD1, but some other form of FALS? From the little information I have, it seems like 50% are carriers, and that 50% of the carriers get sick.
Other information or comments would be much appreciated!
My mother and one of her brothers have / have had ALS och their uncle (mother's brother) probably had it too (diagnosed as MS 40 years ago). My grandmother had 3 siblings. As mentioned, her brother seems to have had ALS and she herself seems to have been a carrier. My mother had 9 brothers and sisters, and is the youngest one of the bunch. Several of the others are well over 80 years old and healthy. My grandmother was 83 when she died.
Does this mean that we don't have the SOD1, but some other form of FALS? From the little information I have, it seems like 50% are carriers, and that 50% of the carriers get sick.
Other information or comments would be much appreciated!